Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy

Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy

Abstract Background Accumulating evidence suggest that autophagy plays a pivotal role in various anticancer therapies, including photodynamic therapy (PDT), acting as a pro-death or pro-survival mechanism in a context-dependent manner. Therefore, we aimed to determine the role of autophagy in Photof...

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Bibliographic Details
Main Authors: Antoni Domagala, Joanna Stachura, Magdalena Gabrysiak, Angelika Muchowicz, Radoslaw Zagozdzon, Jakub Golab, Malgorzata Firczuk
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
Autophagy
Photodynamic therapy
Photofrin
ATG5
CRISR/Cas-9
Online Access:http://link.springer.com/article/10.1186/s12885-018-4126-y

Internet

http://link.springer.com/article/10.1186/s12885-018-4126-y

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