Importance of Bcl-2-family proteins in murine hematopoietic progenitor and early B cells

Abstract Mitochondrial apoptosis regulates survival and development of hematopoietic cells. Prominent roles of some Bcl-2-family members in this regulation have been established, for instance for pro-apoptotic Bim and anti-apoptotic Mcl-1. Additional, mostly smaller roles are known for other Bcl-2-m...

Full description

Bibliographic Details
Main Authors: Constanze Kurschat, Arlena Metz, Susanne Kirschnek, Georg Häcker
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04079-8