Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone

In addition to its well-known abortifacient effect, mifepristone (MIF) has been used as an anticancer drug for various cancers in many studies with an in-depth understanding of the mechanism of action. However, application of MIF is limited by its poor water solubility and low oral bioavailability....

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Bibliographic Details
Main Authors: Huijuan Zhang, Fuqiang Wu, Yazhen Li, Xiping Yang, Jiamei Huang, Tingting Lv, Yingying Zhang, Jianzhong Chen, Haijun Chen, Yu Gao, Guannan Liu, Lee Jia
Format: Article
Language:English
Published: Beilstein-Institut 2016-11-01
Series:Beilstein Journal of Nanotechnology
Subjects:
Online Access:https://doi.org/10.3762/bjnano.7.178