Patterns of evolutionary conservation of essential genes correlate with their compensability.
Essential genes code for fundamental cellular functions required for the viability of an organism. For this reason, essential genes are often highly conserved across organisms. However, this is not always the case: orthologues of genes that are essential in one organism are sometimes not essential i...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-06-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3386227?pdf=render |