A hybrid of B and T lymphoblastic cell line could potentially substitute dendritic cells to efficiently expand out Her-2/neu-specific cytotoxic T lymphocytes from advanced breast cancer patients in vitro

A hybrid of B and T lymphoblastic cell line could potentially substitute dendritic cells to efficiently expand out Her-2/neu-specific cytotoxic T lymphocytes from advanced breast cancer patients in vitro

Abstract Adoptive transfer of cytotoxic T lymphocytes (CTLs) holds promises to cure cancer. However, this treatment is hindered by lacking a robust way to specifically expand out CTLs. Here, we developed a hybrid of B lymphoblastic cell line and T lymphoblastic cell line (T2 cells) as a substitute o...

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Bibliographic Details
Main Authors: Sheng Chen, Feifei Gu, Kang Li, Kai Zhang, Yangyang Liu, Jinyan Liang, Wei Gao, Gang Wu, Li Liu
Format: Article
Language:English
Published: BMC 2017-02-01
Series:Journal of Hematology & Oncology
Subjects:
Hybrid of B and T lymphoblastic cell line
Adoptive cancer immunotherapy
Cytotoxic T lymphocytes
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13045-017-0429-8

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http://link.springer.com/article/10.1186/s13045-017-0429-8

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