PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing

PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing

PolyPurine Reverse Hoogsteen Hairpins (PPRHs) are gene-silencing DNA-oligonucleotides developed in our laboratory that are formed by two antiparallel polypurine mirror repeat domains bound intramolecularly by Hoogsteen bonds. The aim of this work was to explore the feasibility of using viral vectors...

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Bibliographic Details
Main Authors: Eva Aubets, Miguel Chillon, Carlos J. Ciudad, Véronique Noé
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
PPRH
oligonucleotide
survivin
gene targeting
gene silencing
delivery
Online Access:https://www.mdpi.com/1422-0067/22/18/10025

Internet

https://www.mdpi.com/1422-0067/22/18/10025

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