Targeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis.

Although Aurora B is important in cleavage furrow ingression and completion during cytokinesis, the mechanism by which kinase activity is targeted to the cleavage furrow and the molecule(s) responsible for this process have remained elusive. Here, we demonstrate that an essential mitotic kinesin MKl...

Full description

Bibliographic Details
Main Authors: Mayumi Kitagawa, Suet Yin Sarah Fung, Nobuyuki Onishi, Hideyuki Saya, Sang Hyun Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3672163?pdf=render