Flexible docking-based molecular dynamics simulation of natural product compounds and Ebola virus Nucleocapsid (EBOV NP): a computational approach to discover new drug for combating Ebola

Flexible docking-based molecular dynamics simulation of natural product compounds and Ebola virus Nucleocapsid (EBOV NP): a computational approach to discover new drug for combating Ebola

Abstract Background Ebola still remains as one of the most problematic infectious diseases in Africa with a high rate of mortality. Although this disease has been known for an almost half-century, there are no vaccines and drugs available in the market to treat Ebola. Zaire ebolavirus (EBOV), a sing...

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Bibliographic Details
Main Authors: Mochammad Arfin Fardiansyah Nasution, Erwin Prasetya Toepak, Ahmad Husein Alkaff, Usman Sumo Friend Tambunan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Ebola virus
Ebola virus nucleocapsid
Natural product compounds
Virtual screening
Flexible docking
Molecular dynamics simulation
Online Access:http://link.springer.com/article/10.1186/s12859-018-2387-8

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http://link.springer.com/article/10.1186/s12859-018-2387-8

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