Evaluation of inactivated Bordetella pertussis as a delivery system for the immunization of mice with Pneumococcal Surface Antigen A.

Evaluation of inactivated Bordetella pertussis as a delivery system for the immunization of mice with Pneumococcal Surface Antigen A.

Pneumococcal Surface Protein A (PspA) has been successfully tested as vaccine candidate against Streptococcus pneumoniae infections. Vaccines able to induce PspA-specific antibodies and Th1 cytokines usually provide protection in mice. We have shown that the whole cell pertussis vaccine (wP) or comp...

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Bibliographic Details
Main Authors: Julia T Castro, Giuliana S Oliveira, Melissa A Nishigasako, Anne-Sophie Debrie, Eliane N Miyaji, Alessandra Soares-Schanoski, Milena A Akamatsu, Camille Locht, Paulo L Ho, Nathalie Mielcarek, Maria Leonor S Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228055

Internet

https://doi.org/10.1371/journal.pone.0228055

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