MicroRNAs Contribute to Promyelocyte Apoptosis in As2O3-Treated APL Cells

MicroRNAs Contribute to Promyelocyte Apoptosis in As2O3-Treated APL Cells

Background: Arsenic trioxide (As2O3), an ancient drug used in traditional Chinese medicine, has substantial anticancer activities, especially in the treatment of patients suffering from acute promyelocytic leukemia (APL); however the underlying mechanisms are not well understood. Methods: MTT assay...

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Bibliographic Details
Main Authors: Haihai Liang, Xuelian Li, Lu Wang, Shaonan Yu, Zhidan Xu, Yunyan Gu, Zhenwei Pan, Tianyu Li, Meiyu Hu, Hairong Cui, Xue Liu, Ying Zhang, Chaoqian Xu, Rui Guo, Yanjie Lu, Baofeng Yang, Hongli Shan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
As2O3
Acute promyelocytic leukemia
Apoptosis
microRNA
PML
Online Access:http://www.karger.com/Article/FullText/356615

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http://www.karger.com/Article/FullText/356615

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