Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models

Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models

Evodiamine (EVO) and rutaecarpine (RUT) are promising anti-tumor drug candidates. The evaluation of the anti-proliferative activity and cellular uptake of EVO and RUT in 3D multicellular spheroids of cancer cells would better recapitulate the native situation and thus better reflect an in vivo respo...

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Bibliographic Details
Main Authors: Hui Guo, Dongmei Liu, Bin Gao, Xiaohui Zhang, Minli You, Hui Ren, Hongbo Zhang, Hélder A. Santos, Feng Xu
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Molecules
Subjects:
cellular uptake
auto-fluorescence
3D multicellular spheroids
hanging drop method
Online Access:http://www.mdpi.com/1420-3049/21/7/954

Internet

http://www.mdpi.com/1420-3049/21/7/954

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