Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes

Renal tubular injury is a critical factor in the pathogenesis of diabetic nephropathy (DN). Endoplasmic reticulum (ER) stress is involved in diabetic nephropathy. Tauroursodeoxycholic acid (TUDCA) is an effective inhibitor of ER stress. Here, we investigated the role of TUDCA in the progression of t...

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Bibliographic Details
Main Authors: Jing Zhang, Ying Fan, Chuchu Zeng, Li He, Niansong Wang
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/8/10/589