Induction of plasminogen activator inhibitor type-1 (PAI-1) by hypoxia and irradiation in human head and neck carcinoma cell lines

<p>Abstract</p> <p>Background</p> <p>Squamous cell carcinoma of the head and neck (SCCHN) often contain highly radioresistant hypoxic regions, nonetheless, radiotherapy is a common treatment modality for these tumours. Reoxygenation during fractionated radiotherapy is d...

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Bibliographic Details
Main Authors: Mengele Karin, Pruschy Martin, Sweep Fred CGJ, Geurts-Moespot Anneke, Bayer Christine, Schilling Daniela, Sprague Lisa D, Molls Michael
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/143