p66Shc Aging Protein in Control of Fibroblasts Cell Fate

p66Shc Aging Protein in Control of Fibroblasts Cell Fate

Reactive oxygen species (ROS) are wieldy accepted as one of the main factors of the aging process. These highly reactive compounds modify nucleic acids, proteins and lipids and affect the functionality of mitochondria in the first case and ultimately of the cell. Any agent or genetic modification th...

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Bibliographic Details
Main Authors: Mariusz R. Wieckowski, Paolo Pinton, Maciej Pronicki, Jerzy Duszynski, Carlotta Giorgi, Joanna Szczepanowska, Gyorgy Szabadkai, Agnieszka Karkucinska-Wieckowska, Magdalena Lebiedzinska, Jan M. Suski
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:International Journal of Molecular Sciences
Subjects:
p66Shc
reactive oxygen species
antioxidant defense
mitochondria
Online Access:http://www.mdpi.com/1422-0067/12/8/5373/

Internet

http://www.mdpi.com/1422-0067/12/8/5373/

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