In- silico identification of key residues for shifting the coenzyme specificity of an aldehyde-dehidrogenase

The aldehyde dehydrogenase enzyme coded by the pAO1 megaplasmid of A. nicotinovorans has an 35% identity at the sequence level with the succinic-semialdehyde dehydrogenase from E. coli, the latter being a suitable template for homology modeling experiments. The computer generated model of AlDH helpe...

Full description

Bibliographic Details
Main Authors: Marius Mihasan, Vlad Artenie, Zenovia Olteanu
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2010-12-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/833