Furin‐mediated protein processing in infectious diseases and cancer

Abstract Proteolytic cleavage regulates numerous processes in health and disease. One key player is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at polybasic recognition motifs. Mammalian substrates of furin include cytokines, hormones, growth factors and re...

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Bibliographic Details
Main Authors: Elisabeth Braun, Daniel Sauter
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1073