Furin‐mediated protein processing in infectious diseases and cancer
Abstract Proteolytic cleavage regulates numerous processes in health and disease. One key player is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at polybasic recognition motifs. Mammalian substrates of furin include cytokines, hormones, growth factors and re...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | Clinical & Translational Immunology |
Subjects: | |
Online Access: | https://doi.org/10.1002/cti2.1073 |