Human monocytes differentiate into dendritic cells subsets that induce anergic and regulatory T cells in sepsis.

BACKGROUND: Sepsis is a multifactorial pathology with high susceptibility to secondary infections. Innate and adaptive immunity are affected in sepsis, including monocyte deactivation. METHODOLOGY/PRINCIPAL FINDINGS: To better understand the effects of alterations in monocytes on the regulation of i...

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Bibliographic Details
Main Authors: Valérie Faivre, Anne Claire Lukaszewicz, Arnaud Alves, Dominique Charron, Didier Payen, Alain Haziot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3468528?pdf=render