Chronic kidney disease and fibrosis: the role of uremic retention solutes
Chronic kidney disease (CKD) is a major global health concern, and the uremic state is highly associated with fibrogenesis in several organs and tissues. Fibrosis is characterized by excessive production and deposition of extracellular matrix proteins with a detrimental impact on organ function. Ano...
Main Authors: | Henricus A.M. Mutsaers, Elisabeth G.D. Stribos, Griet eGlorieux, Raymond eVanholder, Peter eOlinga |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-08-01
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Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00060/full |
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