Detection of the BRAF V600E Mutation in Colorectal Cancer by NIR Spectroscopy in Conjunction with Counter Propagation Artificial Neural Network

Detection of the BRAF V600E Mutation in Colorectal Cancer by NIR Spectroscopy in Conjunction with Counter Propagation Artificial Neural Network

This paper proposes a sensitive, sample preparation-free, rapid, and low-cost method for the detection of the B-rapidly accelerated fibrosarcoma (BRAF) gene mutation involving a substitution of valine to glutamic acid at codon 600 (V600E) in colorectal cancer (CRC) by near-infrared (NIR) spectroscop...

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Bibliographic Details
Main Authors: Xue Zhang, Yang Yang, Yalan Wang, Qi Fan
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
near-infrared spectroscopy
counter propagation artificial neural network
detection
auxiliary diagnosis
BRAF V600E mutation
colorectal cancer
tissue
paraffin-embedded
deparaffinized
stained
Online Access:https://www.mdpi.com/1420-3049/24/12/2238

Internet

https://www.mdpi.com/1420-3049/24/12/2238

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