Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice

<p>Abstract</p> <p>Background</p> <p>Interleukin-12 (IL-12) is a cytokine well known for its role in immunity. A lesser known function of IL-12 is its role in hematopoiesis. The promising data obtained in the preclinical models of antitumor immunotherapy raised hope tha...

Full description

Bibliographic Details
Main Authors: Miller Joseph D, Shibata Darryl, Gallaher Timothy K, Basile Lena A, Douer Dan
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/26