Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways.

Skin mononuclear phagocytes (MNPs) provide the first interactions of invading viruses with the immune system. In addition to Langerhans cells (LCs), we recently described a second epidermal MNP population, Epi-cDC2s, in human anogenital epidermis that is closely related to dermal conventional dendri...

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Bibliographic Details
Main Authors: Kirstie M Bertram, Naomi R Truong, Jacinta B Smith, Min Kim, Kerrie J Sandgren, Konrad L Feng, Jason J Herbert, Hafsa Rana, Kevin Danastas, Monica Miranda-Saksena, Jake W Rhodes, Ellis Patrick, Ralph C Cohen, Jake Lim, Steven L Merten, Andrew N Harman, Anthony L Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009536