Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients [v2; ref status: indexed, http://f1000r.es/4dh]

Some somatic single nucleotide variants (SNVs) are thought to be pathogenic, leading to neurological disease. We hypothesized that heterogeneous nuclear ribonuclear protein A1 (hnRNP A1), an autoantigen associated with multiple sclerosis (MS) would contain SNVs. MS patients develop antibodies to hnR...

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Bibliographic Details
Main Authors: Sangmin Lee, Michael Levin
Format: Article
Language:English
Published: F1000 Research Ltd 2014-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-132/v2