Genome Replication in Thermococcus kodakarensis Independent of Cdc6 and an Origin of Replication

The initiation of DNA replication is typically tightly regulated by proteins that form initiation complexes at specific sequences known as replication origins. In Archaea and Eukaryotes, Cdc6, a near-universally conserved protein binds and facilitates the origin-dependent assembly of the replicative...

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Bibliographic Details
Main Authors: Alexandra M. Gehring, David P. Astling, Rie Matsumi, Brett W. Burkhart, Zvi Kelman, John N. Reeve, Kenneth L. Jones, Thomas J. Santangelo
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02084/full