The Study of the Structure—Diuretic Activity Relationship in a Series of New N-(Arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo-[3,2,1-ij]quinoline-5-carboxamides

The Study of the Structure—Diuretic Activity Relationship in a Series of New N-(Arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo-[3,2,1-ij]quinoline-5-carboxamides

In accordance with the principles of “me-too” technique, the preparative method for obtaining has been proposed, and the synthesis of a large series of new N-(arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxamides as structurally close analog...

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Bibliographic Details
Main Authors: Igor V. Ukrainets, Mykola Y. Golik, Lyudmila V. Sidorenko, Valentina I. Korniyenko, Lina A. Grinevich, Galina Sim, Olga V. Kryvanych
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2018-08-01
Series:Scientia Pharmaceutica
Subjects:
4-hydroxyquinolin-2(1H)-ones
N-(arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro- 1H-pyrrolo[3,2,1-ij]quinoline-5-carboxamides
pyrroloquinolines
amidation
“me-too” drugs
diuretic activity
Online Access:http://www.mdpi.com/2218-0532/86/3/31

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http://www.mdpi.com/2218-0532/86/3/31

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