Synthesis and propagation of complement C3 by microglia/monocytes in the aging retina.

<h4>Introduction</h4>Complement activation is thought to contribute to the pathogenesis of age-related macular degeneration (AMD), which may be mediated in part by para-inflammatory processes. We aimed to investigate the expression and localization of C3, a crucial component of the compl...

Full description

Bibliographic Details
Main Authors: Matt Rutar, Krisztina Valter, Riccardo Natoli, Jan M Provis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24705166/pdf/?tool=EBI