Chromatin signature of widespread monoallelic expression

Chromatin signature of widespread monoallelic expression

In mammals, numerous autosomal genes are subject to mitotically stable monoallelic expression (MAE), including genes that play critical roles in a variety of human diseases. Due to challenges posed by the clonal nature of MAE, very little is known about its regulation; in particular, no molecular fe...

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Bibliographic Details
Main Authors: Anwesha Nag, Virginia Savova, Ho-Lim Fung, Alexander Miron, Guo-Cheng Yuan, Kun Zhang, Alexander A Gimelbrant
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-12-01
Series:eLife
Subjects:
monoallelic expression
chromatin
epigenome
bivalent
AST-Seq
Online Access:https://elifesciences.org/articles/01256

Internet

https://elifesciences.org/articles/01256

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