Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function
Measures of lung function are heritable, and thus, we sought to utilise genetics to propose drug-repurposing candidates that could improve respiratory outcomes. Lung function measures were found to be genetically correlated with seven druggable biochemical traits, with further evidence of a causal r...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/63115 |