Mutations in Epigenetic Regulation Genes in Gastric Cancer

Mutations in Epigenetic Regulation Genes in Gastric Cancer

We have performed mutational profiling of 25 genes involved in epigenetic processes on 135 gastric cancer (GC) samples. In total, we identified 79 somatic mutations in 49/135 (36%) samples. The minority (<i>n</i> = 8) of mutations was identified in DNA methylation/demethylation genes, wh...

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Bibliographic Details
Main Authors: Marina V. Nemtsova, Alexey I. Kalinkin, Ekaterina B. Kuznetsova, Irina V. Bure, Ekaterina A. Alekseeva, Igor I. Bykov, Tatiana V. Khorobrykh, Dmitry S. Mikhaylenko, Alexander S. Tanas, Vladimir V. Strelnikov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
gastric cancer
epigenetic regulation genes
somatic mutations
molecular genetic markers
Online Access:https://www.mdpi.com/2072-6694/13/18/4586

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https://www.mdpi.com/2072-6694/13/18/4586

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