Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model
Rhabdomyosarcoma is an aggressive childhood malignancy, accounting for more than 50% of all soft-tissue sarcomas in children. Even with extensive therapy, the survival rate among alveolar rhabdomyosarcoma patients with advanced disease is only 20%. The receptor tyrosine kinase Epidermal Growth Facto...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | Sarcoma |
Online Access: | http://dx.doi.org/10.1155/2011/130484 |