Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation

Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation

Abstract Background In the Lophotrochozoa/Spiralia superphylum, few organisms have as high a capacity for rapid testing of gene function and single-cell transcriptomics as the freshwater planaria. The species Schmidtea mediterranea in particular has become a powerful model to use in studying adult s...

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Bibliographic Details
Main Authors: Lakshmipuram Seshadri Swapna, Alyssa M. Molinaro, Nicole Lindsay-Mosher, Bret J. Pearson, John Parkinson
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Genome Biology
Subjects:
Schmidtea mediterranea
Transcriptomics
Metabolism
Single-cell genomics
Metabolic reconstruction
Transcription factors
Online Access:http://link.springer.com/article/10.1186/s13059-018-1498-x

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http://link.springer.com/article/10.1186/s13059-018-1498-x

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