Methamphetamine Blocks Adenosine A<sub>2A</sub> Receptor Activation via Sigma 1 and Cannabinoid CB<sub>1</sub> Receptors

Methamphetamine Blocks Adenosine A<sub>2A</sub> Receptor Activation via Sigma 1 and Cannabinoid CB<sub>1</sub> Receptors

Methamphetamine is, worldwide, one of the most consumed drugs of abuse. One important side effect is neurodegeneration leading to a decrease in life expectancy. The aim of this paper was to check whether the drug affects one of the receptors involved in neurodegeneration/neuroprotection events, name...

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Bibliographic Details
Main Authors: Mireia Casanovas, Irene Reyes-Resina, Alejandro Lillo, Jaume Lillo, Raul López-Arnau, Jorge Camarasa, Elena Escubedo, Gemma Navarro, Rafael Franco
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
G protein-coupled receptor GPCR
striatal neurons
heteromer
drug of abuse
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/22/5/2743

Internet

https://www.mdpi.com/1422-0067/22/5/2743

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