Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors

Summary: Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here...

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Bibliographic Details
Main Authors: Diego López León, Patricia Matthey, Isabelle Fellay, Marianne Blanchard, Denis Martinvalet, Pierre-Yves Mantel, Luis Filgueira, Michael Walch
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301164