Immunotoxins: The Role of the Toxin

Immunotoxins are antibody-toxin bifunctional molecules that rely on intracellular toxin action to kill target cells. Target specificity is determined via the binding attributes of the chosen antibody. Mostly, but not exclusively, immunotoxins are purpose-built to kill cancer cells as part of novel t...

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Bibliographic Details
Main Authors: David FitzGerald, Antonella Antignani
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/5/8/1486