Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

<h4>Background</h4>Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive multisystem disease (systemic LE [SLE]). Genetic association studies have recently identified several st...

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Main Authors: Tiina M Järvinen, Anna Hellquist, Sari Koskenmies, Elisabet Einarsdottir, Jaana Panelius, Taina Hasan, Heikki Julkunen, Leonid Padyukov, Marika Kvarnström, Marie Wahren-Herlenius, Filippa Nyberg, Mauro D'Amato, Juha Kere, Ulpu Saarialho-Kere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151989/?tool=EBI