Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

<h4>Background</h4>Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive multisystem disease (systemic LE [SLE]). Genetic association studies have recently identified several st...

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Main Authors: Tiina M Järvinen, Anna Hellquist, Sari Koskenmies, Elisabet Einarsdottir, Jaana Panelius, Taina Hasan, Heikki Julkunen, Leonid Padyukov, Marika Kvarnström, Marie Wahren-Herlenius, Filippa Nyberg, Mauro D'Amato, Juha Kere, Ulpu Saarialho-Kere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151989/?tool=EBI

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