Identification of DreI as an antiviral factor regulated by RLR signaling pathway.

BACKGROUND:Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) had been demonstrated to prime interferon (IFN) response against viral infection via the conserved RLR signaling in fish, and a novel fish-specific gene, the grass carp reovirus (GCRV)-induced gene 2 (Gig2), had been suggested t...

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Bibliographic Details
Main Authors: Shun Li, Fan Sun, Yi-Bing Zhang, Jian-Fang Gui, Qi-Ya Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3296712?pdf=render