Response of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combined.

Metformin, the most widely prescribed drug for treatment of type 2 diabetes, has been shown to exert significant anticancer effects. Hyperthermia has been known to kill cancer cells and enhance the efficacy of various anti-cancer drugs and radiotherapy. We investigated the combined effects of metfor...

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Bibliographic Details
Main Authors: Hyemi Lee, Heon Joo Park, Chang-Shin Park, Eun-Taex Oh, Bo-Hwa Choi, Brent Williams, Chung K Lee, Chang W Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914884?pdf=render