Systemic mastocytosis with KIT V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcome

Systemic mastocytosis with KIT V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcome

Abstract Background Mastocytosis are rare diseases characterized by an accumulation of clonal mast cells (MCs) in one or multiple organs or tissues. Patients with systemic mastocytosis (SM), whose MCs frequently arbor the activating D816V KIT mutation, may have indolent to aggressive diseases, and t...

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Bibliographic Details
Main Authors: Iolanda Conde-Fernandes, Rita Sampaio, Filipa Moreno, José Palla-Garcia, Maria dos Anjos Teixeira, Inês Freitas, Esmeralda Neves, Maria Jara-Acevedo, Luis Escribano, Margarida Lima
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Mast cells
Systemic mastocytosis
Mast cell activation disorders
Recurrent anaphylaxis
KIT V560G mutation
Disodium cromoglycate
Online Access:http://link.springer.com/article/10.1186/s13223-017-0193-x

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http://link.springer.com/article/10.1186/s13223-017-0193-x

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