Oncogenic seRNA functional activation: a novel mechanism of tumorigenesis

Abstract seRNA is a noncoding RNA (ncRNA) transcribed from active super-enhancer (SE), through which SE exerts biological functions and participates in various physiological and pathological processes. seRNA recruits cofactor, RNA polymerase II and mediator to constitute and stabilize chromatin loop...

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Bibliographic Details
Main Authors: Yuan Tan, Yuejin Li, Faqing Tang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-020-01195-5