Nucleic Acid Sensors Involved in the Recognition of HBV in the Liver–Specific in vivo Transfection Mouse Models—Pattern Recognition Receptors and Sensors for HBV

Cellular innate immune system recognizing pathogen infection is critical for the host defense against viruses. Hepatitis B virus (HBV) is a DNA virus with a unique life cycle whereby the DNA and RNA intermediates present at different phases. However, it is still unclear whether the viral DNA or RNA...

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Bibliographic Details
Main Authors: Chean Ring Leong, Hiroyuki Oshiumi, Takayuki Suzuki, Misako Matsumoto, Tsukasa Seya
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Medical Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3271/3/2/16