Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice

Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice

Alzheimer’s disease (AD) is a progressive brain disorder and complex mechanisms are involved in the physiopathology of AD. However, there is data suggesting that inflammation plays a role in its development and progression. Indeed, some non-steroidal anti-inflammatory drugs, such as meloxicam, which...

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Bibliographic Details
Main Authors: Maria Eduarda Ziani Gutierrez, Anne Suély Pinto Savall, Edina da Luz Abreu, Kelly Ayumi Nakama, Renata Bem Dos Santos, Marina Costa Monteiro Guedes, Daiana Silva Ávila, Cristiane Luchese, Sandra Elisa Haas, Caroline Brandão Quines, Simone Pinton
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; curcumin; cyclooxygenase-2; lipid core nanocapsules; meloxicam; memory; rats; inflammation
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=4;spage=783;epage=789;aulast=Gutierrez

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=4;spage=783;epage=789;aulast=Gutierrez

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