A Polymorphism Within the MBP Gene Is Associated With a Higher Relapse Number in Male Patients of Multiple Sclerosis

A Polymorphism Within the MBP Gene Is Associated With a Higher Relapse Number in Male Patients of Multiple Sclerosis

Myelin basic protein (MBP) is thought to be one of the key autoantigens in multiple sclerosis (MS) development. A recent study described the association of the single nucleotide polymorphism (SNP) rs12959006, within the MBP gene, with a higher risk of relapse and worse prognosis. We aim at studying...

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Bibliographic Details
Main Authors: Laura Espino-Paisán, Teresa Agudo-Jiménez, Isabel Rosales-Martínez, Pilar López-Cotarelo, María Ángel García-Martínez, María Inmaculada Domínguez-Mozo, Silvia Pérez-Pérez, Romina Dieli-Crimi, Manuel Comabella, Elena Urcelay, Roberto Álvarez-Lafuente
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
SNP
HHV-6
myelin basic protein
relapse
sex differences
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00771/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00771/full

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