Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.

Normal development of the respiratory system is essential for survival and is regulated by multiple genes and signaling pathways. Both Tbx4 and Tbx5 are expressed throughout the mesenchyme of the developing lung and trachea; and, although multiple genes are known to be required in the epithelium, on...

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Bibliographic Details
Main Authors: Ripla Arora, Ross J Metzger, Virginia E Papaioannou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3410851?pdf=render