Human CD4 memory T cells can become CD4+IL-9+ T cells.

IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-beta directs mouse CD4(+)CD25(-)CD62L(+) T cells to commit to inflammatory IL-9 producing CD4(+) T cells.Here we show that human inducible regulatory T cells (iTregs) also express IL...

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Bibliographic Details
Main Authors: Prabhakar Putheti, Amit Awasthi, Joyce Popoola, Wenda Gao, Terry B Strom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806834?pdf=render