Challenges in the Design of a T Cell Vaccine in the Context of HIV-1 Diversity

The extraordinary variability of HIV-1 poses a major obstacle to vaccine development. The effectiveness of a vaccine is likely to vary dramatically in different populations infected with different HIV-1 subtypes, unless innovative vaccine immunogens are developed to protect against the range of HIV-...

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Bibliographic Details
Main Authors: Marcel Tongo, Wendy A. Burgers
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/10/3968