Reduced Expression of the Antigen Processing Machinery Components TAP2, LMP2, and LMP7 in Tonsillar and Base of Tongue Cancer and Implications for Clinical Outcome

Reduced Expression of the Antigen Processing Machinery Components TAP2, LMP2, and LMP7 in Tonsillar and Base of Tongue Cancer and Implications for Clinical Outcome

OBJECTIVES: Patients with human papillomavirus (HPV)–positive tonsillar squamous cell carcinoma (TSCC) and base of tongue squamous cell carcinoma (BOTSCC) have a better clinical outcome than those with corresponding HPV-negative tumors. Moreover, there is a strong positive correlation between absen...

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Bibliographic Details
Main Authors: Nikolaos Tertipis, Linnea Haeggblom, Nathalie Grün, Cecilia Nordfors, Anders Näsman, Tina Dalianis, Torbjörn Ramqvist
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523314001235

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http://www.sciencedirect.com/science/article/pii/S1936523314001235

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