Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish

Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish

Summary: Microglia, the tissue-resident macrophages of the CNS, represent major targets for therapeutic intervention in a wide variety of neurological disorders. Efficient reprogramming protocols to generate microglia-like cells in vitro using patient-derived induced pluripotent stem cells will, how...

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Bibliographic Details
Main Authors: Giuliano Ferrero, Christopher B. Mahony, Eléonore Dupuis, Laurent Yvernogeau, Elodie Di Ruggiero, Magali Miserocchi, Marianne Caron, Catherine Robin, David Traver, Julien Y. Bertrand, Valérie Wittamer
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308301

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http://www.sciencedirect.com/science/article/pii/S2211124718308301

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