FGF-2 inhibits TNF-α mediated apoptosis through upregulation of Bcl2-A1 and Bcl-xL in ATDC5 cells

FGF-2 inhibits TNF-α mediated apoptosis through upregulation of Bcl2-A1 and Bcl-xL in ATDC5 cells

FGF-2 is involved in cell survival, proliferation, apoptosis, andangiogenesis in a wide variety of cells. FRGRs, PI3K and MAPkinases are well known mediators of FGF signaling. Despite itsknown roles during many developmental processes, includingosteogenesis, there are few known targets of FGF-2. In...

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Bibliographic Details
Main Authors: Hey-Ryun Kim, Youn-Moo Heo, Kyoung-Il Jeong, Yong-Min Kim, Hae Lan Jang, Kwang-Yeol Lee, Chang-Yeol Yeo, Sung Hoon Kim, Hak-Kyo Lee, Seung-Ryul Kim, Eung-Gook Kim, Joong-Kook Choi
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-05-01
Series:BMB Reports
Subjects:
Apoptosis
ATDC5 cells
Bcl-xL
Bcl2-A1
FGF-2
TNF-α
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS01JTVEMTIwNTI0MjAxOF8lMjgyODctMjkyJTI5Qk1CMTItMDA1LnBkZg==

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