Synthesis of novel technetium-99m tricarbonyl-HBED-CC complexes and structural prediction in solution by density functional theory calculation

Synthesis of novel technetium-99m tricarbonyl-HBED-CC complexes and structural prediction in solution by density functional theory calculation

HBED-CC (N,N'-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylene diamine-N,N'-diacetic acid, L1) is a common bifunctional chelating agent in preparation of 68Ga-radiopharmaceuticals. Due to its high stability constant for the Ga3+ complex (logKGaL = 38.5) and its acyclic structure, it is well k...

Full description

Bibliographic Details
Main Authors: Shengyu Shi, Lifeng Yao, Linlin Li, Zehui Wu, Zhihao Zha, Hank F. Kung, Lin Zhu, De-Cai Fang
Format: Article
Language:English
Published: The Royal Society 2019-11-01
Series:Royal Society Open Science
Subjects:
[99mtc][tc(co)3(h2o)3]+
hbed-cc
structural prediction
density functional theory
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191247

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191247

Similar Items