Macroscopic detection of demyelinated lesions in mouse PNS with neutral red dye

Abstract Lysophosphatidylcholine (LPC)-induced demyelination is a versatile animal model that is frequently used to identify and examine molecular pathways of demyelination and remyelination in the central (CNS) and peripheral nervous system (PNS). However, identification of focally demyelinated les...

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Bibliographic Details
Main Authors: Reiji Yamazaki, Yasuyuki Osanai, Tom Kouki, Yoshiaki Shinohara, Jeffrey K. Huang, Nobuhiko Ohno
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96395-4